Here they are: The 28 ingredients that go into every Knowell capsule, each one selected with intention. Some of these nutrients have been rigorously studied by western scientists, while others have deeper roots in eastern medicine. The one thing they all have in common? Every vitamin, mineral, and botanical we include has the power to influence hormone balance for the better.

Nutritional Information

  • The root and berry of this plant are used in Ayurvedic medicine.
  • Classified as an adaptogen, it can help the body manage stress.
  • Supports healthy blood sugar levels and cortisol response, as well as improved mood.
  • May be beneficial for an underactive thyroid.
Black Pepper
  • Helps promote the absorption and activity of vitamin A and curcumin from turmeric.
  • Powerful antioxidant—helps keep cells healthy for proper hormone function.
  • May aid in digestion.
  • Naturally-occurring enzyme in pineapple and other foods.
  • Aids in digestion.
  • Supports healthy inflammation response after exercise, which is necessary for stable hormones.
  • Antioxidant-rich mushroom found in cold, northern climates.
  • Protects against oxidative stress and promotes healthy inflammation response, which can support hormone function.
  • Fruit of the chaste tree found in the Mediterranean and central Asia.
  • Can help support symptoms associated with PMS.
  • May help to balance mood, irritability, and stress and supports healthy bowel movement.
  • A type of mushroom widely used in traditional Chinese medicine.
  • One of its natural chemicals, cordycepin, may help the body utilize oxygen to support energy, circulation, and libido.
Cranberry Extract
  • Fruit that packs an antioxidant and antibacterial punch.
  • Supports a healthy bladder and urinary tract.
  • An essential trace mineral that’s difficult to find in food sources.
  • Essential for carbohydrate metabolism.
  • May help promote glucose tolerance, fat metabolism, and lean body mass.
Folate B9
  • It is widely recommended that women of reproductive age are encouraged to supplement with folate to avoid birth defects.
  • Folate is essential to building DNA and RNA.
  • Similar in structure to B vitamins—sometimes called B8.
  • Plays a role in healthy insulin activity, which can impact other hormones.
  • Involved in neurotransmitter synthesis and may help support mood and stress response.
  • A radish-like cruciferous vegetable grown in Peru that’s used in cooking and medicine.
  • Rich in flavonoids, which may support mood and memory function.
  • May promote athletic endurance and performance.
  • An essential trace mineral involved in nutrient metabolism.
  • Important for the production of thyroxine, a thyroid hormone that balances appetite, metabolism, and overall hormone function.
  • Supports the efficacy of vitamin C, vitamin E, and vitamin B1.
Niacin B3
  • Niacin helps support healthy looking skin.
  • Essential to create NAD which is involved in every metabolic pathway in the body.
  • Involved in lipid (fat) synthesis, balance, and metabolism.
  • Niacin is essential to support digestive and nervous system functions, therefore deficiency is associated with gut distress and confusion.
Probiotic Blend
  • Bacillus coagulans, lactobacillus fermentum, lactobacillus gasseri, lactobacillus rhamnosus.
  • Helps promote a balanced microbiome for optimal digestive function and nutrient absorption.
  • Supports a healthy immune system for ideal hormone balance.
  • Positively impacts digestive symptoms.
  • Supports healthy neurotransmission and serotonin production for stable mood.
  • Edible mushroom rich in the chemical triterpene.
  • Has calming properties that may promote restful sleep, a balanced mood, stress reduction, and focus.
Rhodiola Rosea
  • Plant grown in cold mountainous regions of Europe, Asia, and the Arctic.
  • May support physical performance and promote mental sharpness.
  • Tested by the National Center for Complementary and Integrative Health and linked with supporting a balanced mood.
  • Powerful antioxidant and important to immunity cells.
  • Involved in DNA synthesis.
Thiamin B1
  • Important in energy transformation and metabolism, especially the breakdown of carbohydrates.
  • B1 deficiency is associated with PMS symptoms such as bloating and cramps.
  • A root closely related to ginger used in cooking and Ayurvedic medicine.
  • Curcuminoids, a naturally occurring chemical in turmeric, have been shown to support healthy inflammation response.
Vitamin A
  • A powerful antioxidant that helps to neutralize harmful free radicals.
  • Antioxidant actions helps provide protection to the delicate lipid membranes of cells, maintaining cell integrity.
  • Retinols, circulating forms of vitamin A in the body, support healthy skin.
  • Necessary for the creation of thyroid hormones.
  • Is involved in gene expression and important to reproductive development.
  • Vitamin A is important for the maintenance of the absorptive and secretive epithelium tissues used to exchange fluids and chemicals in the kidneys, pancreas, blood vessels, and small intestine.
Vitamin B6
  • Important to immunity, renal health, and fluid balance.
  • Serves as a co-factor to activate chemicals such as serotonin, adrenaline, and dopamine. Therefore, B6 deficiency is associated with PMS symptoms such as bloating and cramps.
  • Functions as a coenzyme to over 100 enzymes in the body.
Vitamin B12
  • Essential to forming erythroblasts which are building blocks of red blood cells. Deficiency is associated with anemia which menstruating women are more prone to.
  • B12 supports functions of B6 and Folate.
Vitamin C
  • Essential to collagen formation for healthy skin and strong connective tissue.
  • Powerful antioxidant that protects cells and tissues from harmful free radicals.
  • Involved in the synthesis of neurotransmitters such as dopamine and serotonin.
  • Helps the absorption of Iron.
Vitamin D3
  • Both a nutrient and a hormone.
  • Used in the body to make hormones from cholesterol.
  • Essential to building healthy bone and bone maintenance.
  • Balances sodium and calcium levels.
  • Zinc and estrogen are closely linked, and low levels of zinc are associated with irregular ovulation and minor conditions associated with PMS.
  • Is a catalyst for the activity of 50 different enzymes in the body.
  • Important to DNA and gene expression.
  • Active in immune cells to differentiate invaders and inactive them.
  • Found in structural support of tissues materials.