Why should you take Knowell?

Knowell’s formula was created to nourish all aspects of women’s reproductive health. Your reproductive system and hormones are intrinsically linked and when even one of your hormones is out of balance, it creates a ripple effect that can upset the entire system. This can result in problematic and often painful PMS symptoms, irregular periods, fertility issues, mood swings, chronic fatigue, weight gain, skin and hair issues. (And that’s just the beginning.)

There are many reasons why a woman’s hormone health may be less than ideal, but nutrient deficiencies are one major factor. That’s where Knowell comes in. It provides the nutritional foundation that allows your hormones to flourish.

Our supplement is designed to support you, whether you are trying to make PMS less problematic, regulate your cycle, counterbalance the side-effects of the pill, optimize your efforts while trying to conceive or manage the symptoms of PCOS.  Knowell is for all women who want to work with their hormones, not fight against them. 

  • Vegetarian
  • Non-Soy
  • Non-GMO
  • Gluten Free
  • Made in USA

One capsule, 28 ingredients

Our intention was to create the most complete supplement on the market to support women’s reproductive health—and we’re so proud of what we accomplished. Every capsule is home to 28 synergistic ingredients, all thoughtfully chosen and precisely dosed to optimize your everyday.

Get to know our ingredients

B Vitamins

Thiamin B1 • Niacin B3 • Vit B6 • Folate B9 • Vit B12.

Transform food into fuel so you get the most from your healthy diet—essential for hormone system function.

Thiamin B1 - 1.2mg • Niacin B3 - 16mg • Vit B6 - 1.7mg • Folate B9 - 200mcg DFE • Vit B12 - 2.4mcg.


Vit C • Vit A • Turmeric • Black Pepper.

Protect and repair all cells to prevent early signs of aging, while nourishing the thyroid and amping up the effects of nutrients.

Vit C - 100mg • Vit A - 1350 mcg • Turmeric - 150mg • Black Pepper - 10mg.


Zinc • Chromium • Selenium • Manganese.

Involved in brain signaling, immune system function, and maintaining regular periods.

Zinc - 11mg • Chromium - 35mcg • Selenium - 100mcg • Manganese - 2.3mg.

Vitamin D3

Vitamin D3.

The building block for all hormones: You might say D3 is the hardest-working vitamin in the game. Helps maintain healthy skin and strong bones.

Vitamin D3 - 50mcg.



Supports neurotransmitter production in the brain while also optimizing ovarian function and balancing blood sugar. (See ya, sweet cravings.)

Myo-Inositol - 600mg.

Adaptogenic Herbs, Roots, and Plants

Ashwagandha • Chasteberry • Maca • Rhodiola Rosea.

Help the body adapt to stress, giving you the mojo to tackle your work day and workouts. Invigorate the libido and ease symptoms associated with PMS.

Ashwagandha - 250mg • Chasteberry - 250mg • Maca - 200mg • Rhodiola Rosea - 100mg.


Chaga • Cordyceps • Reishi.

Adapt to your body’s needs, promoting immune support, restful sleep, and sustainable energy without the crash.

Chaga - 50mg • Cordyceps - 50mg • Reishi - 50mg.

Probiotics and Enzymes

Bromelain • Bacillus Coagulans • Lactobacillus Rhamnosus • Lactobacillus Fermentum • Lactobacillus Gasseri.

A happy gut equals a healthy immune system, better mood, balanced digestion, and optimal nutrient absorption.

Bromelain - 100mg • Bacillus Coagulans - 133mg • Lactobacillus Rhamnosus - 50mg • Lactobacillus Fermentum - 20mg • Lactobacillus Gasseri - 5mg.



Sweet, tart, and smart! Trusted for years to boost urinary tract health, thanks to powerful antioxidant and antibacterial properties.

Cranberry - 100mg.

Nutritional Information

Customer Reviews
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United States United States

Genuinely Recommend

I have tried a lot of vitamins, and combination of vitamins (probiotics combined with b, magnesium, multi-bites, etc.). I struggle with hormonal imbalances (acne, mood swings, etc), have a stressful job and am prone to some low-level, steady anxiety. These vitamins were recommended to me by my SIL, and I honestly wasn’t expecting much. I was spending $50/month for probiotics only, which I was unwilling to keep doing. I liked that knowell came in under that and had probiotics. I finished a bottle or two (forgot to cancel my subscription), can’t say I noticed anything one way or the other. So I stopped taking them for a month or two. Then I really noticed that my mood swings and general anxiety seemed worse (again- I’ll try almost any vitamin, but have never stuck with one). I decided to give knowell another try and really payed attention. It does noticeably help my mood/hormonal imbalances- I just hadn’t noticed until I stopped taking them. Okay, I thought, even it was placebo- worth it. Then I moved and my CC expired same month. Fast forward 2 months and I hadn’t been taking them. The sides of my lips kept cracking. At first I thought it was just classic dry winter lips, but for the life of me I couldn’t heal them. I’d heal one, then open my mouth in the morning and the other side would crack, etc. I started googling it because it was going on a month and it was SO annoying and looked gross, too. I googled and it said that it could be a vitamin deficiency. Queue ordering knowell again… this is now my “will never stop taking”. My lips had been cracking on the sides for a fuuuull month (lovely, I know). Within less than a week of starting knowell again they healed 90%, many a week they stopped cracking. Anyway, long review, but all to say I’m someone who will try a lot of wellness stuff, but nothing ever lives up to the hype. Knowell absolutely has for me.

United States United States

Changed my life!

My psychiatrist recommended Knowell supplements after I told him about my irregular periods and extreme depression. He suspected that my hormones levels were creating the depression, irritability and constant fatigue that I was experiencing. Literally less than a week after I started taking these, the fatigue and brain fog I had been experiencing for months went away. This supplement is not a cure all, but it has really changed my life!! I’ve also noticed better skin and improved libido. Amazing supplement, can’t recommend it enough!!

A Knowell Customer
United States United States

Returned Period (after 4 years)!!

I decided to try this after losing my period back in 2019 once I came off the pill. I had been diagnosed with hypothalamic amennorhea. I significantly cut back exercise, increased food, and even tried HRT. HRT temporarily helped bring back menstruation - but it instantly went away after I stopped taking it. After about ~1 month and 1 week, I got my first natural period!! I had experimented with NAC and Chasteberry alone for months with no results. Thank you!!!!

Courtney G.
United States United States


These pills are really easy to digest and I saw a huge difference in my cycle this month. I have always dealt with my inconsistencies in my cycle, but this month is came right on time with less irritation. I have been taking sole myo- instinol for a few months but decided to switch to Knowell bc of the other supplements and vitamins that are included all in one pill!

Madison H.
United States United States

Works Wonders

So far, my experience taking knowell has been hugely helpful to the menstrual struggles I have with my condition of PCOS. I am currently on a journey of no brith control and it’s been helping me naturally deal with my menstruation and it’s giving me confidence of fertility in my future.

Only the best for your hormones

Our ingredient standards border on obsessive, and we promise to deliver you the highest-quality supplements, always.

Knowell is made in the USA at a cGMP, FDA-registered facility. (Translation: The best of the best.) We carefully test all ingredients at every step of the production process to guarantee the utmost purity. What you see on the ingredient list is what you get.


Not all multi-vitamins are created equal - I can tell you that this supplement passes all of my supplement scrutinies!!  

Dr Erin Kinney

It's got the right ingredients to support estrogen balance, metabolism, healthy gut, and stress reduction!

Callie Exas RDN